The focus of our research program is the restoration of limb function through a biohybrid approach. We consider the limb conceptually as a biohybrid organ con-sisting of biological tissue, endoprostheses (including neural devices and joint replacements), and exopro-stheses. The biohybrid limb maximizes biological function and functional articulations with optimized hu-manprosthesis interfaces. Our long-term goals are to create biomimetic prostheses, optimized control systems for pros-theses, and optimized human-prosthesis interfaces using both limb lengthening and osseointegration techniques.

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