Robot-assisted rehabilitation is an active area of research in the field of stroke rehabilitation. RUPERT is a wearable roboticexoskeleton powered by pneumatic muscle actuators. In this study, we described the structure of the controllers for the five degrees of freedom currently used by RUPERT. We applied the RUPERT on 6 stroke patients to provide robot-assisted rehabilitation therapy in a clinical study. Statistical χ² test on the proportion of successfully reaching targets showed that 3 out of the 6 patients demonstrated significant improvement in reaching targets successfully, and the remaining 3 did not show performance improvement or deterioration. We plan to implement the RUPERT in the patient’s house for easier access and more frequent use. More significant performance results are expected.

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