This chapter presents an experimental study of upper-limb surface EMG signals and two cases of applying surface EMG signals to control an upper-limb exoskeleton robot. The applied method to process surface EMG signals to use as input information to the control method is also explained. At first, surface EMG signal extraction method and processing method are presented in this chap-ter. Then, the upper-limb muscle activities during daily upper-limb motions have been studied to enable exoskeleton robots to estimate human upper-limb motions based on EMG signals of related muscles. The muscle combinations are identified to separate some motions of upper-limb. Minimum number of muscles to extract signals to control frequent daily upper-limb motions has been identified. In the next step, EMG signal of identified muscles are used to control two upper-limb exoskeleton robots. A three degree of freedom (DOF) exoskeleton robot (W-EXOS) for the forearm pronation/supination, wrist flexion/extension and ulnar/radial deviation are controlled by applying the surface EMG signals of six muscles. Surface EMG signals of upper-limb muscles are applied as input information to control a 6DOF exoskeleton robot (SUEFUL-6). In each case of applying EMG signals experiments have been carried out to evaluate the effectiveness of the EMG based control method.

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